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Oocyte age and preconceptual alcohol use are highly correlated with epigenetic imprinting of a noncoding RNA (nc886)

Genomic imprinting occurs before fertilization, impacts every cell of the developing child, and may be sensitive to environmental perturbations. The noncoding RNA, nc886 (also called VTRNA2-1) is the only known example of the ∼100 human genes imprinted by DNA methylation, that shows polymorphic impr...

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Detalles Bibliográficos
Autores principales: Carpenter, Brittany L., Remba, Tanaka K., Thomas, Stacey L., Madaj, Zachary, Brink, Lucy, Tiedemann, Rochelle L., Odendaal, Hein J., Jones, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000112/
https://www.ncbi.nlm.nih.gov/pubmed/33723081
http://dx.doi.org/10.1073/pnas.2026580118