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Oocyte age and preconceptual alcohol use are highly correlated with epigenetic imprinting of a noncoding RNA (nc886)
Genomic imprinting occurs before fertilization, impacts every cell of the developing child, and may be sensitive to environmental perturbations. The noncoding RNA, nc886 (also called VTRNA2-1) is the only known example of the ∼100 human genes imprinted by DNA methylation, that shows polymorphic impr...
Autores principales: | Carpenter, Brittany L., Remba, Tanaka K., Thomas, Stacey L., Madaj, Zachary, Brink, Lucy, Tiedemann, Rochelle L., Odendaal, Hein J., Jones, Peter A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000112/ https://www.ncbi.nlm.nih.gov/pubmed/33723081 http://dx.doi.org/10.1073/pnas.2026580118 |
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