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CTLA-2 Alpha Is a Potent Inhibitor of Angiogenesis in Murine Ocular Tissue

Cytotoxic T lymphocyte antigen-2 (CTLA-2) alpha has been reported to suppress the activities of cathepsin L (Cath L), which is deeply involved in angiogenesis. Therefore, we assessed whether CTLA-2 alpha plays a role in angiogenesis in ocular tissue. To establish models of corneal inflammation and e...

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Detalles Bibliográficos
Autores principales: Maruyama, Kazuichi, Yoneda, Kazuhito, Sugita, Sunao, Yamamoto, Yoshimi, Koike, Masato, Peters, Christoph, Uchiyama, Yasuo, Nishida, Kohji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000157/
https://www.ncbi.nlm.nih.gov/pubmed/33804126
http://dx.doi.org/10.3390/antiox10030456