NTRK Fusions in Sarcomas: Diagnostic Challenges and Clinical Aspects

Tropomyosin receptor kinase (TK) is encoded by the neurotrophic tyrosine receptor kinase genes (NTRK) 1, 2, and 3, whose activation plays an important role in cell cycle proliferation and survival. Fusions of one of these genes can lead to constitutive activation of TRK, which can potentially be onc...

Descripción completa

Detalles Bibliográficos
Autores principales: Siozopoulou, Vasiliki, Smits, Evelien, De Winne, Koen, Marcq, Elly, Pauwels, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000177/
https://www.ncbi.nlm.nih.gov/pubmed/33803146
http://dx.doi.org/10.3390/diagnostics11030478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000177/
https://www.ncbi.nlm.nih.gov/pubmed/33803146
http://dx.doi.org/10.3390/diagnostics11030478

Ejemplares similares