One or two injections of MVA-vectored vaccine shields hACE2 transgenic mice from SARS-CoV-2 upper and lower respiratory tract infection

Modified vaccinia virus Ankara (MVA) is a replication-restricted smallpox vaccine, and numerous clinical studies of recombinant MVAs (rMVAs) as vectors for prevention of other infectious diseases, including COVID-19, are in progress. Here, we characterize rMVAs expressing the S protein of severe acu...

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Detalles Bibliográficos
Autores principales: Liu, Ruikang, Americo, Jeffrey L., Cotter, Catherine A., Earl, Patricia L., Erez, Noam, Peng, Chen, Moss, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000198/
https://www.ncbi.nlm.nih.gov/pubmed/33688035
http://dx.doi.org/10.1073/pnas.2026785118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000198/
https://www.ncbi.nlm.nih.gov/pubmed/33688035
http://dx.doi.org/10.1073/pnas.2026785118

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