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One or two injections of MVA-vectored vaccine shields hACE2 transgenic mice from SARS-CoV-2 upper and lower respiratory tract infection
Modified vaccinia virus Ankara (MVA) is a replication-restricted smallpox vaccine, and numerous clinical studies of recombinant MVAs (rMVAs) as vectors for prevention of other infectious diseases, including COVID-19, are in progress. Here, we characterize rMVAs expressing the S protein of severe acu...
Autores principales: | Liu, Ruikang, Americo, Jeffrey L., Cotter, Catherine A., Earl, Patricia L., Erez, Noam, Peng, Chen, Moss, Bernard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000198/ https://www.ncbi.nlm.nih.gov/pubmed/33688035 http://dx.doi.org/10.1073/pnas.2026785118 |
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