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Agonistic CD40 Antibodies in Cancer Treatment

SIMPLE SUMMARY: CD40 is a costimulatory molecule that is key for the activation of antigen-presenting cells and other innate immune cells. It plays an important role in anti-tumor immunity, and agonists of CD40 have been shown to eliminate tumors in both pre-clinical and clinical settings, alone and...

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Detalles Bibliográficos
Autores principales: Djureinovic, Dijana, Wang, Meina, Kluger, Harriet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000216/
https://www.ncbi.nlm.nih.gov/pubmed/33804039
http://dx.doi.org/10.3390/cancers13061302