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Biosensors for Biogenic Amines: A Review

Biogenic amines (BAs) are well-known biomolecules, mostly for their toxic and carcinogenic effects. Commonly, they are used as an indicator of quality preservation in food and beverages since their presence in higher concentrations is associated with poor quality. With respect to BA’s metabolic path...

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Autores principales: Vasconcelos, Helena, Coelho, Luís C. C., Matias, Ana, Saraiva, Cristina, Jorge, Pedro A. S., de Almeida, José M. M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000219/
https://www.ncbi.nlm.nih.gov/pubmed/33805834
http://dx.doi.org/10.3390/bios11030082
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author Vasconcelos, Helena
Coelho, Luís C. C.
Matias, Ana
Saraiva, Cristina
Jorge, Pedro A. S.
de Almeida, José M. M. M.
author_facet Vasconcelos, Helena
Coelho, Luís C. C.
Matias, Ana
Saraiva, Cristina
Jorge, Pedro A. S.
de Almeida, José M. M. M.
author_sort Vasconcelos, Helena
collection PubMed
description Biogenic amines (BAs) are well-known biomolecules, mostly for their toxic and carcinogenic effects. Commonly, they are used as an indicator of quality preservation in food and beverages since their presence in higher concentrations is associated with poor quality. With respect to BA’s metabolic pathways, time plays a crucial factor in their formation. They are mainly formed by microbial decarboxylation of amino acids, which is closely related to food deterioration, therefore, making them unfit for human consumption. Pathogenic microorganisms grow in food without any noticeable change in odor, appearance, or taste, thus, they can reach toxic concentrations. The present review provides an overview of the most recent literature on BAs with special emphasis on food matrixes, including a description of the typical BA assay formats, along with its general structure, according to the biorecognition elements used (enzymes, nucleic acids, whole cells, and antibodies). The extensive and significant amount of research that has been done to the investigation of biorecognition elements, transducers, and their integration in biosensors, over the years has been reviewed.
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spelling pubmed-80002192021-03-28 Biosensors for Biogenic Amines: A Review Vasconcelos, Helena Coelho, Luís C. C. Matias, Ana Saraiva, Cristina Jorge, Pedro A. S. de Almeida, José M. M. M. Biosensors (Basel) Review Biogenic amines (BAs) are well-known biomolecules, mostly for their toxic and carcinogenic effects. Commonly, they are used as an indicator of quality preservation in food and beverages since their presence in higher concentrations is associated with poor quality. With respect to BA’s metabolic pathways, time plays a crucial factor in their formation. They are mainly formed by microbial decarboxylation of amino acids, which is closely related to food deterioration, therefore, making them unfit for human consumption. Pathogenic microorganisms grow in food without any noticeable change in odor, appearance, or taste, thus, they can reach toxic concentrations. The present review provides an overview of the most recent literature on BAs with special emphasis on food matrixes, including a description of the typical BA assay formats, along with its general structure, according to the biorecognition elements used (enzymes, nucleic acids, whole cells, and antibodies). The extensive and significant amount of research that has been done to the investigation of biorecognition elements, transducers, and their integration in biosensors, over the years has been reviewed. MDPI 2021-03-13 /pmc/articles/PMC8000219/ /pubmed/33805834 http://dx.doi.org/10.3390/bios11030082 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Review
Vasconcelos, Helena
Coelho, Luís C. C.
Matias, Ana
Saraiva, Cristina
Jorge, Pedro A. S.
de Almeida, José M. M. M.
Biosensors for Biogenic Amines: A Review
title Biosensors for Biogenic Amines: A Review
title_full Biosensors for Biogenic Amines: A Review
title_fullStr Biosensors for Biogenic Amines: A Review
title_full_unstemmed Biosensors for Biogenic Amines: A Review
title_short Biosensors for Biogenic Amines: A Review
title_sort biosensors for biogenic amines: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000219/
https://www.ncbi.nlm.nih.gov/pubmed/33805834
http://dx.doi.org/10.3390/bios11030082
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