6-Azauridine Induces Autophagy-Mediated Cell Death via a p53- and AMPK-Dependent Pathway

6-Azauridine (6-AZA), a pyrimidine nucleoside analogue, is known to exhibit both antitumor and antiviral activities. Although 6-AZA was discovered more than 60 years ago, the cellular effects of this compound are yet to be elucidated. Here, we report that 6-AZA regulates autophagy-mediated cell deat...

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Detalles Bibliográficos
Autores principales: Cha, Yeo-Eun, Park, Rackhyun, Jang, Minsu, Park, Yea-In, Yamamoto, Ayane, Oh, Won Keun, Lee, Eun-Ju, Park, Junsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000275/
https://www.ncbi.nlm.nih.gov/pubmed/33799444
http://dx.doi.org/10.3390/ijms22062947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000275/
https://www.ncbi.nlm.nih.gov/pubmed/33799444
http://dx.doi.org/10.3390/ijms22062947

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