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6-Azauridine Induces Autophagy-Mediated Cell Death via a p53- and AMPK-Dependent Pathway
6-Azauridine (6-AZA), a pyrimidine nucleoside analogue, is known to exhibit both antitumor and antiviral activities. Although 6-AZA was discovered more than 60 years ago, the cellular effects of this compound are yet to be elucidated. Here, we report that 6-AZA regulates autophagy-mediated cell deat...
Autores principales: | Cha, Yeo-Eun, Park, Rackhyun, Jang, Minsu, Park, Yea-In, Yamamoto, Ayane, Oh, Won Keun, Lee, Eun-Ju, Park, Junsoo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000275/ https://www.ncbi.nlm.nih.gov/pubmed/33799444 http://dx.doi.org/10.3390/ijms22062947 |
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