Evaluation of Beta-Catenin Subcellular Localization and Water Channel Protein AQP1 Expression as Predictive Markers of Chemo-Resistance in Ovarian High-Grade Serous Carcinoma: Comparative Study between Preoperative Peritoneal Biopsies and Surgical Samples

Background. Mutations of the β-catenin gene (CTNNB1), leading to aberrant immunohistochemical expression of β-catenin, represent a key mechanism of WNT/β-catenin pathway alteration in ovarian cancer. Aquaporin 1 (AQP1), as component of transmembrane-water-channel family proteins, has been documented...

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Detalles Bibliográficos
Autores principales: Angelico, Giuseppe, Ieni, Antonio, Caltabiano, Rosario, Santoro, Angela, Inzani, Frediano, Spadola, Saveria, Tuccari, Giovanni, Macrì, Antonio, Zannoni, Gian Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000296/
https://www.ncbi.nlm.nih.gov/pubmed/33807998
http://dx.doi.org/10.3390/diagnostics11030452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000296/
https://www.ncbi.nlm.nih.gov/pubmed/33807998
http://dx.doi.org/10.3390/diagnostics11030452

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