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Deciphering the Role of Residues Involved in Disorder-To-Order Transition Regions in Archaeal tRNA Methyltransferase 5

tRNA methyltransferase 5 (Trm5) enzyme is an S-adenosyl methionine (AdoMet)-dependent methyltransferase which methylates the G37 nucleotide at the N(1) atom of the tRNA. The free form of Trm5 enzyme has three intrinsically disordered regions, which are highly flexible and lack stable three-dimension...

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Detalles Bibliográficos
Autores principales: Srivastava, Ambuj, Yesudhas, Dhanusha, Ahmad, Shandar, Gromiha, M. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000304/
https://www.ncbi.nlm.nih.gov/pubmed/33799704
http://dx.doi.org/10.3390/genes12030399