A Novel Validated Injectable Colistimethate Sodium Analysis Combining Advanced Chemometrics and Design of Experiments

Colistimethate sodium (CMS) is widely administrated for the treatment of life-threatening infections caused by multidrug-resistant Gram-negative bacteria. Until now, the quality control of CMS formulations has been based on microbiological assays. Herein, an ultra-high-performance liquid chromatogra...

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Detalles Bibliográficos
Autores principales: Dagla, Ioanna, Tsarbopoulos, Anthony, Gikas, Evagelos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000333/
https://www.ncbi.nlm.nih.gov/pubmed/33799846
http://dx.doi.org/10.3390/molecules26061546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000333/
https://www.ncbi.nlm.nih.gov/pubmed/33799846
http://dx.doi.org/10.3390/molecules26061546

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