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Dual Inhibition of AKT and MEK Pathways Potentiates the Anti-Cancer Effect of Gefitinib in Triple-Negative Breast Cancer Cells

SIMPLE SUMMARY: Triple-negative breast cancer (TNBC) is an intractable subset of breast cancer without an efficient therapeutic strategy due to the lack of tractable targets, such as the estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2. Activation and/or amplifi...

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Detalles Bibliográficos
Autores principales: You, Kyu Sic, Yi, Yong Weon, Cho, Jeonghee, Seong, Yeon-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000364/
https://www.ncbi.nlm.nih.gov/pubmed/33801977
http://dx.doi.org/10.3390/cancers13061205