A conformational switch driven by phosphorylation regulates the activity of the evolutionarily conserved SNARE Ykt6

Ykt6 is a soluble N-ethylmaleimide sensitive factor activating protein receptor (SNARE) critically involved in diverse vesicular fusion pathways. While most SNAREs rely on transmembrane domains for their activity, Ykt6 dynamically cycles between the cytosol and membrane-bound compartments where it i...

Descripción completa

Detalles Bibliográficos
Autores principales: McGrath, Kaitlyn, Agarwal, Shivani, Tonelli, Marco, Dergai, Mykola, Gaeta, Anthony L., Shum, Andrew K., Lacoste, Jessica, Zhang, Yongbo, Wen, Wenyu, Chung, Daayun, Wiersum, Grant, Shevade, Aishwarya, Zaichick, Sofia, van Rossum, Damian B., Shuvalova, Ludmilla, Savas, Jeffrey N., Kuchin, Sergei, Taipale, Mikko, Caldwell, Kim A., Caldwell, Guy A., Fasshauer, Dirk, Caraveo, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000380/
https://www.ncbi.nlm.nih.gov/pubmed/33723042
http://dx.doi.org/10.1073/pnas.2016730118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000380/
https://www.ncbi.nlm.nih.gov/pubmed/33723042
http://dx.doi.org/10.1073/pnas.2016730118

Ejemplares similares