Inhibition of NUPR1–Karyopherin β1 Binding Increases Anticancer Drug Sensitivity

Background: Nuclear protein-1 (NUPR1, also known as p8/Com-1) is a transcription factor involved in the regulation of cellular stress responses, including serum starvation and drug stimulation. Methods: We investigated the mechanism of NUPR1 nuclear translocation involving karyopherin β1 (KPNB1), us...

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Detalles Bibliográficos
Autores principales: Park, Chanhee, Oh, Jiwon, Lee, Won Mo, Koh, Hye Ran, Sohn, Uy Dong, Ham, Seung Wook, Oh, Kyungsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000408/
https://www.ncbi.nlm.nih.gov/pubmed/33801927
http://dx.doi.org/10.3390/ijms22062794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000408/
https://www.ncbi.nlm.nih.gov/pubmed/33801927
http://dx.doi.org/10.3390/ijms22062794

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