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Inhibition of NUPR1–Karyopherin β1 Binding Increases Anticancer Drug Sensitivity
Background: Nuclear protein-1 (NUPR1, also known as p8/Com-1) is a transcription factor involved in the regulation of cellular stress responses, including serum starvation and drug stimulation. Methods: We investigated the mechanism of NUPR1 nuclear translocation involving karyopherin β1 (KPNB1), us...
Autores principales: | Park, Chanhee, Oh, Jiwon, Lee, Won Mo, Koh, Hye Ran, Sohn, Uy Dong, Ham, Seung Wook, Oh, Kyungsoo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000408/ https://www.ncbi.nlm.nih.gov/pubmed/33801927 http://dx.doi.org/10.3390/ijms22062794 |
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