Cargando…

A safe and highly efficacious measles virus-based vaccine expressing SARS-CoV-2 stabilized prefusion spike

The current pandemic of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) highlights an urgent need to develop a safe, efficacious, and durable vaccine. Using a measles virus (rMeV) vaccine strain as the backbone, we developed a series of recombinant attenuated vaccine...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Mijia, Dravid, Piyush, Zhang, Yuexiu, Trivedi, Sheetal, Li, Anzhong, Harder, Olivia, KC, Mahesh, Chaiwatpongsakorn, Supranee, Zani, Ashley, Kenney, Adam, Zeng, Cong, Cai, Chuanxi, Ye, Chengjin, Liang, Xueya, Shimamura, Masako, Liu, Shan-Lu, Mejias, Asuncion, Ramilo, Octavio, Boyaka, Prosper N., Qiu, Jianming, Martinez-Sobrido, Luis, Yount, Jacob S., Peeples, Mark E., Kapoor, Amit, Niewiesk, Stefan, Li, Jianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000430/
https://www.ncbi.nlm.nih.gov/pubmed/33688034
http://dx.doi.org/10.1073/pnas.2026153118