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Managing Difficulties of Microsatellite Instability Testing in Endometrial Cancer-Limitations and Advantages of Four Different PCR-Based Approaches

SIMPLE SUMMARY: Due to the approval of immune checkpoint inhibitor therapy for microsatellite instability-high or mismatch repair-deficient advanced solid tumors, testing of both biomarkers has gained interest in recent years. Available testing systems were established in the context of Lynch Syndro...

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Detalles Bibliográficos
Autores principales: Siemanowski, Janna, Schömig-Markiefka, Birgid, Buhl, Theresa, Haak, Anja, Siebolts, Udo, Dietmaier, Wolfgang, Arens, Norbert, Pauly, Nina, Ataseven, Beyhan, Büttner, Reinhard, Merkelbach-Bruse, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000432/
https://www.ncbi.nlm.nih.gov/pubmed/33809329
http://dx.doi.org/10.3390/cancers13061268