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Immunoediting role for major vault protein in apoptotic signaling induced by bacterial N-acyl homoserine lactones

The major vault protein (MVP) mediates diverse cellular responses, including cancer cell resistance to chemotherapy and protection against inflammatory responses to Pseudomonas aeruginosa. Here, we report the use of photoactive probes to identify MVP as a target of the N-(3-oxo-dodecanoyl) homoserin...

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Detalles Bibliográficos
Autores principales: Rayo, Josep, Gregor, Rachel, Jacob, Nicholas T., Dandela, Rambabu, Dubinsky, Luba, Yashkin, Alex, Aranovich, Alexander, Thangaraj, Manikandan, Ernst, Orna, Barash, Eran, Malitsky, Sergey, Florea, Bogdan I., Krom, Bastiaan P., Wiemer, Erik A. C., Kickhoefer, Valerie A., Rome, Leonard H., Mathison, John C., Kaufmann, Gunnar F., Overkleeft, Herman S., Cravatt, Benjamin F., Zor, Tsaffrir, Janda, Kim D., Ulevitch, Richard J., Kravchenko, Vladimir V., Meijler, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000436/
https://www.ncbi.nlm.nih.gov/pubmed/33723037
http://dx.doi.org/10.1073/pnas.2012529118