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Immunoediting role for major vault protein in apoptotic signaling induced by bacterial N-acyl homoserine lactones
The major vault protein (MVP) mediates diverse cellular responses, including cancer cell resistance to chemotherapy and protection against inflammatory responses to Pseudomonas aeruginosa. Here, we report the use of photoactive probes to identify MVP as a target of the N-(3-oxo-dodecanoyl) homoserin...
Autores principales: | Rayo, Josep, Gregor, Rachel, Jacob, Nicholas T., Dandela, Rambabu, Dubinsky, Luba, Yashkin, Alex, Aranovich, Alexander, Thangaraj, Manikandan, Ernst, Orna, Barash, Eran, Malitsky, Sergey, Florea, Bogdan I., Krom, Bastiaan P., Wiemer, Erik A. C., Kickhoefer, Valerie A., Rome, Leonard H., Mathison, John C., Kaufmann, Gunnar F., Overkleeft, Herman S., Cravatt, Benjamin F., Zor, Tsaffrir, Janda, Kim D., Ulevitch, Richard J., Kravchenko, Vladimir V., Meijler, Michael M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000436/ https://www.ncbi.nlm.nih.gov/pubmed/33723037 http://dx.doi.org/10.1073/pnas.2012529118 |
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