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Hydrolysis of Extracellular ATP by Vascular Smooth Muscle Cells Transdifferentiated into Chondrocytes Generates P(i) but Not PP(i)

(1) Background: Tissue non-specific alkaline phosphatase (TNAP) is suspected to induce atherosclerosis plaque calcification. TNAP, during physiological mineralization, hydrolyzes the mineralization inhibitor inorganic pyrophosphate (PP(i)). Since atherosclerosis plaques are characterized by the pres...

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Detalles Bibliográficos
Autores principales: Buchet, Rene, Tribes, Camille, Rouaix, Valentine, Doumèche, Bastien, Fiore, Michele, Wu, Yuqing, Magne, David, Mebarek, Saida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000465/
https://www.ncbi.nlm.nih.gov/pubmed/33799449
http://dx.doi.org/10.3390/ijms22062948