Developing a Yeast Platform Strain for an Enhanced Taxadiene Biosynthesis by CRISPR/Cas9

Paclitaxel is an important diterpenoid commonly used as an anticancer drug. Although the paclitaxel biosynthetic pathway has been mostly revealed, some steps remain to be elucidated. The difficulties in plant transformations and the scarcity of the precursor of paclitaxel, (+)-taxa-4(5), 11(12)-dien...

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Detalles Bibliográficos
Autores principales: Utomo, Joseph C., Chaves, Fabio C., Bauchart, Philippe, Martin, Vincent J. J., Ro, Dae-Kyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000486/
https://www.ncbi.nlm.nih.gov/pubmed/33802586
http://dx.doi.org/10.3390/metabo11030147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000486/
https://www.ncbi.nlm.nih.gov/pubmed/33802586
http://dx.doi.org/10.3390/metabo11030147

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