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N-Acetyl Cysteine Overdose Inducing Hepatic Steatosis and Systemic Inflammation in Both Propacetamol-Induced Hepatotoxic and Normal Mice

Acetaminophen (APAP) overdose induces acute liver damage and even death. The standard therapeutic dose of N-acetyl cysteine (NAC) cannot be applied to every patient, especially those with high-dose APAP poisoning. There is insufficient evidence to prove that increasing NAC dose can treat patients wh...

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Detalles Bibliográficos
Autores principales: Liou, Gunn-Guang, Hsieh, Cheng-Chi, Lee, Yi-Ju, Li, Pin-Hung, Tsai, Ming-Shiun, Li, Chi-Ting, Wang, Sue-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000488/
https://www.ncbi.nlm.nih.gov/pubmed/33809388
http://dx.doi.org/10.3390/antiox10030442