A New Anti-Estrogen Discovery Platform Identifies FDA-Approved Imidazole Anti-Fungal Drugs as Bioactive Compounds against ERα Expressing Breast Cancer Cells

17β-estradiol (E2) exerts its physiological effects through the estrogen receptor α (i.e., ERα). The E2:ERα signaling allows the regulation of cell proliferation. Indeed, E2 sustains the progression of ERα positive (ERα+) breast cancers (BCs). The presence of ERα at the BC diagnosis drives their the...

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Detalles Bibliográficos
Autores principales: Cipolletti, Manuela, Bartoloni, Stefania, Busonero, Claudia, Parente, Martina, Leone, Stefano, Acconcia, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000495/
https://www.ncbi.nlm.nih.gov/pubmed/33805656
http://dx.doi.org/10.3390/ijms22062915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000495/
https://www.ncbi.nlm.nih.gov/pubmed/33805656
http://dx.doi.org/10.3390/ijms22062915

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