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A New Anti-Estrogen Discovery Platform Identifies FDA-Approved Imidazole Anti-Fungal Drugs as Bioactive Compounds against ERα Expressing Breast Cancer Cells

17β-estradiol (E2) exerts its physiological effects through the estrogen receptor α (i.e., ERα). The E2:ERα signaling allows the regulation of cell proliferation. Indeed, E2 sustains the progression of ERα positive (ERα+) breast cancers (BCs). The presence of ERα at the BC diagnosis drives their the...

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Detalles Bibliográficos
Autores principales:	Cipolletti, Manuela, Bartoloni, Stefania, Busonero, Claudia, Parente, Martina, Leone, Stefano, Acconcia, Filippo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000495/ https://www.ncbi.nlm.nih.gov/pubmed/33805656 http://dx.doi.org/10.3390/ijms22062915

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