RAS Nanoclusters: Dynamic Signaling Platforms Amenable to Therapeutic Intervention

RAS proteins are mutated in approximately 20% of all cancers and are generally associated with poor clinical outcomes. RAS proteins are localized to the plasma membrane and function as molecular switches, turned on by partners that receive extracellular mitogenic signals. In the on-state, they activ...

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Detalles Bibliográficos
Autores principales: Van, Que N., Prakash, Priyanka, Shrestha, Rebika, Balius, Trent E., Turbyville, Thomas J., Stephen, Andrew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000715/
https://www.ncbi.nlm.nih.gov/pubmed/33802474
http://dx.doi.org/10.3390/biom11030377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000715/
https://www.ncbi.nlm.nih.gov/pubmed/33802474
http://dx.doi.org/10.3390/biom11030377

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