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RAS Nanoclusters: Dynamic Signaling Platforms Amenable to Therapeutic Intervention
RAS proteins are mutated in approximately 20% of all cancers and are generally associated with poor clinical outcomes. RAS proteins are localized to the plasma membrane and function as molecular switches, turned on by partners that receive extracellular mitogenic signals. In the on-state, they activ...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000715/ https://www.ncbi.nlm.nih.gov/pubmed/33802474 http://dx.doi.org/10.3390/biom11030377 |