Trans-Epithelial Transport, Metabolism, and Biological Activity Assessment of the Multi-Target Lupin Peptide LILPKHSDAD (P5) and Its Metabolite LPKHSDAD (P5-Met)

P5 (LILPKHSDAD) is a hypocholesterolemic peptide from lupin protein with a multi-target activity, since it inhibits both 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCoAR) and proprotein convertase subtilisin/kexin type-9 (PCSK9). This work shows that, during epithelial transport experiments,...

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Detalles Bibliográficos
Autores principales: Lammi, Carmen, Aiello, Gilda, Bollati, Carlotta, Li, Jianqiang, Bartolomei, Martina, Ranaldi, Giulia, Ferruzza, Simonetta, Fassi, Enrico Mario Alessandro, Grazioso, Giovanni, Sambuy, Yula, Arnoldi, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000724/
https://www.ncbi.nlm.nih.gov/pubmed/33808034
http://dx.doi.org/10.3390/nu13030863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000724/
https://www.ncbi.nlm.nih.gov/pubmed/33808034
http://dx.doi.org/10.3390/nu13030863

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