Prevention of Postprandial Hyperglycemia by Ophthalmic Nanoparticles Based on Protamine Zinc Insulin in the Rabbit

Postprandial hyperglycemia, a so-called blood glucose spike, is associated with enhanced risks of diabetes mellitus (DM) and its complications. In this study, we attempted to design nanoparticles (NPs) of protamine zinc insulin (PZI) by the bead mill method, and prepare ophthalmic formulations based...

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Detalles Bibliográficos
Autores principales: Deguchi, Saori, Ogata, Fumihiko, Isaka, Takumi, Otake, Hiroko, Nakazawa, Yosuke, Kawasaki, Naohito, Nagai, Noriaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000746/
https://www.ncbi.nlm.nih.gov/pubmed/33809008
http://dx.doi.org/10.3390/pharmaceutics13030375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000746/
https://www.ncbi.nlm.nih.gov/pubmed/33809008
http://dx.doi.org/10.3390/pharmaceutics13030375

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