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Rolipram Prevents the Formation of Abdominal Aortic Aneurysm (AAA) in Mice: PDE4B as a Target in AAA

Abdominal aortic aneurysm (AAA) is a common life-threatening condition characterized by exacerbated inflammation and the generation of reactive oxygen species. Pharmacological treatments to slow AAA progression or to prevent its rupture remain a challenge. Targeting phosphodiesterase 4 (PDE4) has be...

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Detalles Bibliográficos
Autores principales: Varona, Saray, Puertas, Lídia, Galán, María, Orriols, Mar, Cañes, Laia, Aguiló, Silvia, Camacho, Mercedes, Sirvent, Marc, Andrés, Vicente, Martínez-González, José, Rodríguez, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000788/
https://www.ncbi.nlm.nih.gov/pubmed/33809405
http://dx.doi.org/10.3390/antiox10030460