Synthesis, Anticonvulsant, and Antinociceptive Activity of New 3-(2-Chlorophenyl)- and 3-(3-Chlorophenyl)-2,5-dioxo-pyrrolidin-1-yl-acetamides

The new series of 3-(2-chlorophenyl)- and 3-(3-chlorophenyl)-pyrrolidine-2,5-dione-acetamide derivatives as potential anticonvulsant and analgesic agents was synthesized. The compounds obtained were evaluated in the following acute models of epilepsy: maximal electroshock (MES), psychomotor (6 Hz, 3...

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Detalles Bibliográficos
Autores principales: Góra, Małgorzata, Czopek, Anna, Rapacz, Anna, Gębska, Anna, Wójcik-Pszczoła, Katarzyna, Pękala, Elżbieta, Kamiński, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000848/
https://www.ncbi.nlm.nih.gov/pubmed/33809109
http://dx.doi.org/10.3390/molecules26061564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000848/
https://www.ncbi.nlm.nih.gov/pubmed/33809109
http://dx.doi.org/10.3390/molecules26061564

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