Effect of Reducing Ataxia-Telangiectasia Mutated (ATM) in Experimental Autosomal Dominant Polycystic Kidney Disease

The DNA damage response (DDR) pathway is upregulated in autosomal dominant polycystic kidney disease (ADPKD) but its functional role is not known. The ataxia-telangiectasia mutated (ATM) and AT and Rad3-related (ATR) protein kinases are key proximal transducers of the DDR. This study hypothesized th...

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Detalles Bibliográficos
Autores principales: Zhang, Jennifer Q. J., Saravanabavan, Sayanthooran, Rangan, Gopala K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000896/
https://www.ncbi.nlm.nih.gov/pubmed/33802342
http://dx.doi.org/10.3390/cells10030532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000896/
https://www.ncbi.nlm.nih.gov/pubmed/33802342
http://dx.doi.org/10.3390/cells10030532

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