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Generating a Precision Endoxifen Prediction Algorithm to Advance Personalized Tamoxifen Treatment in Patients with Breast Cancer

Tamoxifen is an endocrine treatment for hormone receptor positive breast cancer. The effectiveness of tamoxifen may be compromised in patients with metabolic resistance, who have insufficient metabolic generation of the active metabolites endoxifen and 4-hydroxy-tamoxifen. This has been challenging...

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Detalles Bibliográficos
Autores principales: Helland, Thomas, Alsomairy, Sarah, Lin, Chenchia, Søiland, Håvard, Mellgren, Gunnar, Hertz, Daniel Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000933/
https://www.ncbi.nlm.nih.gov/pubmed/33805613
http://dx.doi.org/10.3390/jpm11030201