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Polymer-Supported Synthesis of Various Pteridinones and Pyrimidodiazepinones

In this report, we employed the solid-phase synthetic approach to prepare variously substituted dihydropteridinones, tetrahydropyrrolopteridinones, and pyrimidodiazepinones, using a versatile building block-4,6-dichloro-5-nitropyrimidine. All these compounds are pharmacologically significant scaffol...

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Detalles Bibliográficos
Autores principales: Chasák, Jan, Brulíková, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000973/
https://www.ncbi.nlm.nih.gov/pubmed/33799340
http://dx.doi.org/10.3390/molecules26061603