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Targeting Chronic Myeloid Leukemia Stem/Progenitor Cells Using Venetoclax-Loaded Immunoliposome

SIMPLE SUMMARY: Chronic myeloid leukemia stem cells (CML LSCs) are a rare and quiescent population that are resistant to tyrosine kinase inhibitors. CML LSCs have many features in common with hematopoietic stem cells (HSCs) and selectively targeting this population and sparing HSCs is of paramount i...

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Detalles Bibliográficos
Autores principales: Houshmand, Mohammad, Garello, Francesca, Stefania, Rachele, Gaidano, Valentina, Cignetti, Alessandro, Spinelli, Michela, Fava, Carmen, Nikougoftar Zarif, Mahin, Galimberti, Sara, Pungolino, Ester, Annunziata, Mario, Luciano, Luigia, Specchia, Giorgina, Bocchia, Monica, Binotto, Gianni, Bonifacio, Massimiliano, Martino, Bruno, Pregno, Patrizia, Stagno, Fabio, Iurlo, Alessandra, Russo, Sabina, Aime, Silvio, Circosta, Paola, Saglio, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000981/
https://www.ncbi.nlm.nih.gov/pubmed/33804056
http://dx.doi.org/10.3390/cancers13061311