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Probing the Structure and Function of the Cytosolic Domain of the Human Zinc Transporter ZnT8 with Nickel(II) Ions
The human zinc transporter ZnT8 provides the granules of pancreatic β-cells with zinc (II) ions for assembly of insulin hexamers for storage. Until recently, the structure and function of human ZnTs have been modelled on the basis of the 3D structures of bacterial zinc exporters, which form homodime...
Autores principales: | Catapano, Maria Carmen, Parsons, Douglas S., Kotuniak, Radosław, Mladěnka, Přemysl, Bal, Wojciech, Maret, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000985/ https://www.ncbi.nlm.nih.gov/pubmed/33799326 http://dx.doi.org/10.3390/ijms22062940 |
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