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The Immune Tolerance Role of the HMGB1-RAGE Axis

The disruption of the immune tolerance induces autoimmunity such as systemic lupus erythematosus and vasculitis. A chromatin-binding non-histone protein, high mobility group box 1 (HMGB1), is released from the nucleus to the extracellular milieu in particular environments such as autoimmunity, sepsi...

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Detalles Bibliográficos
Autores principales: Watanabe, Haruki, Son, Myoungsun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001022/
https://www.ncbi.nlm.nih.gov/pubmed/33807604
http://dx.doi.org/10.3390/cells10030564