Analysis of Sequence Divergence in Mammalian ABCGs Predicts a Structural Network of Residues That Underlies Functional Divergence

The five members of the mammalian G subfamily of ATP-binding cassette transporters differ greatly in their substrate specificity. Four members of the subfamily are important in lipid transport and the wide substrate specificity of one of the members, ABCG2, is of significance due to its role in mult...

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Detalles Bibliográficos
Autores principales: Mitchell-White, James I., Stockner, Thomas, Holliday, Nicholas, Briddon, Stephen J., Kerr, Ian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001107/
https://www.ncbi.nlm.nih.gov/pubmed/33809494
http://dx.doi.org/10.3390/ijms22063012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001107/
https://www.ncbi.nlm.nih.gov/pubmed/33809494
http://dx.doi.org/10.3390/ijms22063012

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