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Analysis of Sequence Divergence in Mammalian ABCGs Predicts a Structural Network of Residues That Underlies Functional Divergence
The five members of the mammalian G subfamily of ATP-binding cassette transporters differ greatly in their substrate specificity. Four members of the subfamily are important in lipid transport and the wide substrate specificity of one of the members, ABCG2, is of significance due to its role in mult...
Autores principales: | Mitchell-White, James I., Stockner, Thomas, Holliday, Nicholas, Briddon, Stephen J., Kerr, Ian D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001107/ https://www.ncbi.nlm.nih.gov/pubmed/33809494 http://dx.doi.org/10.3390/ijms22063012 |
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