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Synthesis of Michael Adducts as Key Building Blocks for Potential Analgesic Drugs: In vitro, in vivo and in silico Explorations

BACKGROUND: Organocatalytic asymmetric Michael addition is a strong approach for C-C bond formation. The objective of the study is to design molecules by exploiting the efficiency of Michael Adducts. We proceeded with the synthesis of Michael adducts by tailoring the substitution pattern on maleimid...

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Detalles Bibliográficos
Autores principales: Ahmad, Sajjad, Mahnashi, Mater H, Alyami, Bandar A, Alqahtani, Yahya S, Ullah, Farhat, Ayaz, Muhammad, Tariq, Muhammad, Sadiq, Abdul, Rashid, Umer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001115/
https://www.ncbi.nlm.nih.gov/pubmed/33790541
http://dx.doi.org/10.2147/DDDT.S292826