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Downregulation of Circ_0071589 Suppresses Cisplatin Resistance in Colorectal Cancer by Regulating the MiR-526b-3p/KLF12 Axis

BACKGROUND: Chemoresistance is one key factor for the failure of cisplatin (CDDP)-based therapy in colorectal cancer (CRC). Although circular RNAs (circRNAs) are associated with chemoresistance development, the role and mechanism of hsa_circ_0071589 (circ_0071589) in the development of CDDP resistan...

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Detalles Bibliográficos
Autores principales: Zhang, Weitong, Wang, Zhenfen, Cai, Guohao, Huang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001125/
https://www.ncbi.nlm.nih.gov/pubmed/33790646
http://dx.doi.org/10.2147/CMAR.S294880