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Beneficial Impacts of Incorporating the Non-Natural Amino Acid Azulenyl-Alanine into the Trp-Rich Antimicrobial Peptide buCATHL4B

Antimicrobial peptides (AMPs) present a promising scaffold for the development of potent antimicrobial agents. Substitution of tryptophan by non-natural amino acid Azulenyl-Alanine (AzAla) would allow studying the mechanism of action of AMPs by using unique properties of this amino acid, such as abi...

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Detalles Bibliográficos
Autores principales: D’Souza, Areetha R., Necelis, Matthew R., Kulesha, Alona, Caputo, Gregory A., Makhlynets, Olga V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001250/
https://www.ncbi.nlm.nih.gov/pubmed/33809374
http://dx.doi.org/10.3390/biom11030421