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Beneficial Impacts of Incorporating the Non-Natural Amino Acid Azulenyl-Alanine into the Trp-Rich Antimicrobial Peptide buCATHL4B
Antimicrobial peptides (AMPs) present a promising scaffold for the development of potent antimicrobial agents. Substitution of tryptophan by non-natural amino acid Azulenyl-Alanine (AzAla) would allow studying the mechanism of action of AMPs by using unique properties of this amino acid, such as abi...
Autores principales: | D’Souza, Areetha R., Necelis, Matthew R., Kulesha, Alona, Caputo, Gregory A., Makhlynets, Olga V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001250/ https://www.ncbi.nlm.nih.gov/pubmed/33809374 http://dx.doi.org/10.3390/biom11030421 |
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