Eicosapentaenoic Acid Inhibits KRAS Mutant Pancreatic Cancer Cell Growth by Suppressing Hepassocin Expression and STAT3 Phosphorylation

Background: The oncogenic Kirsten rat sarcoma viral oncogene homolog (KRAS) mutation was reported to be the signature genetic event in most cases of pancreatic ductal adenocarcinoma (PDAC). Hepassocin (HPS/FGL1) is involved in regulating lipid metabolism and the progression of several cancer types;...

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Detalles Bibliográficos
Autores principales: Chiu, Ching-Feng, Hsu, Ming-I, Yeh, Hsiu-Yen, Park, Ji Min, Shen, Yu-Shiuan, Tung, Te-Hsuan, Huang, Jun-Jie, Wu, Hung-Tsung, Huang, Shih-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001293/
https://www.ncbi.nlm.nih.gov/pubmed/33801246
http://dx.doi.org/10.3390/biom11030370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001293/
https://www.ncbi.nlm.nih.gov/pubmed/33801246
http://dx.doi.org/10.3390/biom11030370

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