Pyrvinium Treatment Confers Hepatic Metabolic Benefits via β-catenin Downregulation and AMPK Activation

Genetic evidence has indicated that β-catenin plays a vital role in glucose and lipid metabolism. Here, we investigated whether pyrvinium, an anthelmintic agent previously reported as a down-regulator of cellular β-catenin levels, conferred any metabolic advantages in treatment of metabolic disorder...

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Detalles Bibliográficos
Autores principales: Zhou, Shiwei, Obianom, Obinna N., Huang, Jiangsheng, Guo, Dong, Yang, Hong, Li, Qing, Shu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001320/
https://www.ncbi.nlm.nih.gov/pubmed/33806415
http://dx.doi.org/10.3390/pharmaceutics13030330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001320/
https://www.ncbi.nlm.nih.gov/pubmed/33806415
http://dx.doi.org/10.3390/pharmaceutics13030330

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