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High Intrinsic Expression of P-glycoprotein and Breast Cancer Resistance Protein in Canine Mammary Carcinomas Regardless of Immunophenotype and Outcome

SIMPLE SUMMARY: Multidrug resistance of neoplastic cells to chemotherapeutic drugs is a phenomenon mediated by several molecular mechanisms. Among these, P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP) counteract the intracellular load of multiple drugs, preventing their efficacy....

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Detalles Bibliográficos
Autores principales: Levi, Michela, Muscatello, Luisa Vera, Brunetti, Barbara, Benazzi, Cinzia, Parenti, Federico, Gobbo, Francesca, Avallone, Giancarlo, Bacci, Barbara, Zambon, Elisa, Valenti, Paola, Sarli, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001331/
https://www.ncbi.nlm.nih.gov/pubmed/33801360
http://dx.doi.org/10.3390/ani11030658