Dieckol Ameliorates Aβ Production via PI3K/Akt/GSK-3β Regulated APP Processing in SweAPP N2a Cell

The proteolytic processing of amyloid precursor protein (APP) by β-secretase (BACE1) and γ-secretase releases amyloid-β peptide (Aβ), which deposits in amyloid plaques and contributes to the initial causative events of Alzheimer’s disease (AD). In the present study, the regulatory mechanism of APP p...

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Detalles Bibliográficos
Autores principales: Yoon, Jeong-Hyun, Lee, Nayoung, Youn, Kumju, Jo, Mi Ra, Kim, Hyeung-Rak, Lee, Dong-Seok, Ho, Chi-Tang, Jun, Mira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001366/
https://www.ncbi.nlm.nih.gov/pubmed/33804171
http://dx.doi.org/10.3390/md19030152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001366/
https://www.ncbi.nlm.nih.gov/pubmed/33804171
http://dx.doi.org/10.3390/md19030152

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