Cargando…

Metal-Bound Methisazone; Novel Drugs Targeting Prophylaxis and Treatment of SARS-CoV-2, a Molecular Docking Study

SARS-CoV-2 currently lacks effective first-line drug treatment. We present promising data from in silico docking studies of new Methisazone compounds (modified with calcium, Ca; iron, Fe; magnesium, Mg; manganese, Mn; or zinc, Zn) designed to bind more strongly to key proteins involved in replicatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdelaal Ahmed Mahmoud M. Alkhatip, Ahmed, Georgakis, Michail, Montero Valenzuela, Lucio R., Hamza, Mohamed, Farag, Ehab, Hodgkinson, Jaqui, Hosny, Hisham, Kamal, Ahmed M., Wagih, Mohamed, Naguib, Amr, Yassin, Hany, Algameel, Haytham, Elayashy, Mohamed, Abdelhaq, Mohamed, Younis, Mohamed I., Mohamed, Hassan, Abdulshafi, Mohammed, Elramely, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001373/
https://www.ncbi.nlm.nih.gov/pubmed/33804129
http://dx.doi.org/10.3390/ijms22062977