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Targeting BCL-2 in Cancer: Advances, Challenges, and Perspectives
SIMPLE SUMMARY: Apoptosis, a programmed form of cell death, represents the main mechanism by which cells die. Such phenomenon is highly regulated by the BCL-2 family of proteins, which includes both pro-apoptotic and pro-survival proteins. The decision whether cells live or die is tightly controlled...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001391/ https://www.ncbi.nlm.nih.gov/pubmed/33799470 http://dx.doi.org/10.3390/cancers13061292 |