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Targeting BCL-2 in Cancer: Advances, Challenges, and Perspectives

SIMPLE SUMMARY: Apoptosis, a programmed form of cell death, represents the main mechanism by which cells die. Such phenomenon is highly regulated by the BCL-2 family of proteins, which includes both pro-apoptotic and pro-survival proteins. The decision whether cells live or die is tightly controlled...

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Detalles Bibliográficos
Autores principales: Hafezi, Shirin, Rahmani, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001391/
https://www.ncbi.nlm.nih.gov/pubmed/33799470
http://dx.doi.org/10.3390/cancers13061292